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11 Best Mushroom Supplements for Brain Health (2024)

You're probably reading this because you're looking to give your brain a natural boost. You may have focus, memory, or general brain fog issues or want to take a proactive approach to supporting brain health and cognitive function as you age. Whatever your motivations, medicinal mushroom supplements could be a total game-changer. But what are the best mushroom supplements for brain health?

We’ll cut right to the chase — medicinal mushrooms pack some serious brain-boosting powers. Studies show they can improve memory, sharpen concentration, encourage neurogenesis, and protect you against age-related cognitive decline. Pretty impressive for a bunch of fungi, right?

The key lies in mushroom varieties like Lion's mane, Reishi, Cordyceps, and others that have been revered in Eastern medicine for centuries. These little fruiting bodies contain many adaptogen compounds that act as antioxidants, reduce inflammation, and provide a score of brain-boosting benefits.

But with so many mushroom supplement options, finding a quality product can be overwhelming. As bespoke mushroom gummy producers, we’ve spent hours researching and testing the top mushroom-derived dietary supplements. Here, we narrow our recommendation list down to the 11 best for maximizing brain health and cognitive function. Let's dive in!

Best Mushroom Supplements for Brain Health — Goomz Mushroom Gummies

bag of GOOMZ Focus Energy Gummies in Pineapple Lemonade flavor

If you want to boost your brain power with a fun, tasty routine, our gummies offer a delicious way to get your daily dose of functional mushrooms. Goomz mushroom gummies for brain health are worth a try if you’re mushroom-curious — but don’t just take our word for it.

These aren't your typical gummies — they're packed with a potent blend of mushrooms of many varieties, including Lion's mane, Reishi, and Cordyceps.

So, what are mushroom gummies? They’re firm, gelatinous, candy-flavored treats packed with neurotrophic goodness. What sets Goomz Gummies apart is our commitment to using high-quality mushroom extracts and absolutely zero fillers or artificial junk — just real mushrooms in a delicious, guilt-free form.

We've got four unique flavors to satisfy any taste buds — Berry Blast, Strawberry, Watermelon, and Blue Raspberry.

Eat one or two, and you can expect a nice mood boost, heightened senses, and mental clarity. You’ll feel a burst of energy without feeling the crash or jitters later.

Some people even report a creative spark and more exploratory, mindful thought patterns. Just be sure to start low with only one or two gummies to assess your tolerance.

Whether you want to microdose four days on, three off, or take them less frequently, Goomz gummies make it easy to add functional mushrooms into your daily routine for cognitive health.

Shop Goomz Gummies here

Real Mushrooms Lion’s Mane Cognition

bottle of Real Mushrooms Lion's Mane Cognition

Real Mushrooms Lion’s Mane Mushroom Cognition capsules are made from 100% certified organic Lion's mane mushrooms and are one of the best mushroom supplements for cognitive function. These capsules contain no grains, mycelium, or other fillers — just the good stuff.

The hot water extraction process Real Mushrooms uses makes these capsules very effective. It helps make the beneficial compounds in Lion's mane, one of the best mushrooms for the brain, more bioavailable and potent. Each capsule is guaranteed to contain at least 30% beta-glucans, an impressively high load of these potent adaptogens.

We’re also big fans of Real Mushrooms' product transparency. The company’s Lion's mane capsules are third-party tested to ensure quality, and marketing materials are very clear about where the organic mushrooms are sourced and how they're processed. There is no shady business here.

Lion's mane is a fantastic mushroom, whether you want to improve mental clarity and focus, boost your memory, or just capture some functional mushroom benefits for cognitive health and healthy brain aging. Real Mushrooms makes getting a pure Lion's mane supplement you can trust easy.

Shop Real Mushrooms Lion’s Mane Cognition here

Host Defense MycoBotanicals Brain & Body

jar of Host Defense Mushrooms MycoBotanicals Brain and Body supplement powder

Host Defense's MycoBotanicals Brain & Body powder is worth considering if you’re trying to improve your overall cognitive well-being. As one of the best mushroom supplements for cognitive function, this unique formula combines extracts of two potent mushroom varieties: Lion's mane for brain health and focus, plus reishi to promote cardiovascular vitality.

Host Defense has rounded out this potent mushroom blend with herbs like turmeric, ginger, cassia, and black pepper, which have been used for centuries in traditional medicine and are found in some of the best mushroom supplements for brain function.

Turmeric provides anti-inflammatory benefits to support healthy joints, while ginger aids digestion and immune system function. Cassia helps maintain healthy blood sugar levels, and black pepper enhances the absorption of all those good-for-you nutrients.

What we really like about this Lion’s mane mushroom supplement for brain health is that it's powered by mushroom mycelium with no fillers or additives. Its mild flavor can be hidden in smoothies, coffee, flavored beverages, or any comestible, making it easy to incorporate into your everyday routine.

Shop Host Defense MycoBotanicals Brain & Body here

Wholesun Wellness Deep Brain Health Mushroom Blend

a bottle of Wholesun Wellness Deep Brain Health Mushroom Blend

Wholesun Wellness Deep Brain Health Mushroom Blend combines some of the most revered mushroom varieties in powder and capsule form. When you ingest it, you're getting a potent dose of Lion's mane, which has been studied extensively for its ability to promote cognitive function while enhancing focus and concentration.

The Lion’s mane is paired with Reishi mushroom to provide compounds vital to overall brain health, wellness support, and antioxidant processes.

Rounding out the blend are medicinal mushrooms like Cordyceps to fight fatigue, Chaga for immune system function, and Turkey tail, which shows anti-aging potential. Finally, you get Shitake, Oyster, Tremella, Black Fungus, and Poria mushroom essences to help improve your mental clarity.

What we like about this product is that Wholesun Wellness uses certified organic mushroom extracts with no fillers or additives. It's just pure medicinal mushrooms optimized for bioavailability and efficacy.

Whether you want to stay mentally sharp as you age or are just seeking a cognitive boost, this brain-focused mushroom blend is a high-quality option to consider.

Shop Wholesun Wellness Deep Brain Health Mushroom Blend here

The Genius Brand Genius Mushrooms

a jar of The Genius Brand's Genius Mushrooms with 90 count veggie capsules

If you're looking to unlock your brain’s full potential through the power of mushrooms, Genius Mushrooms from The Genius Brand are some of the best mushroom supplement capsules for brain health. They contain a trio of organic mushroom extracts — Lion's Mane, Reishi, and Cordyceps — each with unique benefits.

These vegan pills contain a good amount of Lion’s mane, the star for cognitive enhancement and neuroprotection. It contains compounds that stimulate the growth of brain cells (neurogenesis) and protect existing neurons.

It stood out to us how immaculate this product is. You're getting pure mushroom extracts without fillers, carriers, or artificial ingredients. This product is the perfect delivery method for seamlessly integrating mushroom supplementation into any keto, paleo, or vegan diet.

Shop The Genius Brand's Genius Mushrooms here

Stonehenge Health Dynamic Mushrooms

bottle of Stonehenge Health Dynamic Mushrooms

Stonehenge Health Dynamic Mushrooms capsules pack an impressive 1,400 mg blend of extracts from Lion's Mane, Reishi, Chaga, Shiitake, and Maitake mushrooms into every pill. The Dynamic Mushrooms formula is an excellent choice for supporting brain health.

These veggie capsules are a versatile supplement for brain health, cognitive function, stress response, immune system function, and more.

One of the main reasons we recommend Stonehenge as one of the best brands for brain health mushroom supplements is that its products don't contain any fillers or unnecessary byproducts, which can potentially dilute the effects of any beneficial compounds.

Shop Stonehenge Health Dynamic Mushrooms here

Purify Life World’s First 10-Plex Mushroom Gummies

bottle of Purify Life Mushroom Gummies with Lion's Mane in Natural Raspberry flavor

Purify Life World’s First 10-Plex Mushroom Gummies offer a convenient and delicious way to get your daily dose of functional mushrooms. These tasty raspberry gummies pack small doses of ten different mushroom extracts into each serving!

These gummies are excellent for supporting brain health and improving cognitive function, as they include several mushroom varieties known for cognitive benefits.

You're getting heavy hitters like Lion's mane for brain support and cognitive function, Reishi for immune health, Cordyceps for natural energy, and Turkey tail's antioxidant punch. Purify Life also includes Maitake, Shiitake, Chaga, and even unique varieties like Black fungus and Royal sun. It's an all-in-one mushroom supplement powerhouse.

What we love about these mushroom gummies for focus is how accessible they make it to get your daily dose of mushrooms. The natural raspberry flavor is so good kids — yes, they are safe for kids — and adults alike will enjoy them. Plus, they're pectin-based, vegan, and free of all the junk you might expect, like gelatin, gluten, and GMOs.

Shop Purify Life Mushroom Gummies here

Hello Health Happy Brain Mushroom Complex

hello health happy brain mushroom complex bottle 60 capsules

When it comes to mushroom supplements for cognitive performance, Hello Health's Happy Brain Mushroom Complex goes above and beyond. Its formula contains ten different mushroom species, each delivering specific benefits to support brain health and overall cognitive function.

You get Lion’s mane to stimulate the nerve growth factor that boosts your mental focus and protects against neurodegeneration. You also get Reishi to promote a balanced brain environment and Cordyceps to enhance oxygen utilization.

What we love about this blend is that you cover all bases from all angles regarding cognitive support and brain health. Whether you want to feel sharper and improve mental clarity or stave off age-related brain health decline, Hello Health has you covered.

Shop Hello Health Happy Brain Mushroom Complex here

FreshCap Ultimate Mushroom Complex

a bottle of FreshCap Ultimate Mushroom Complex

FreshCap's Ultimate Mushroom Complex is a solid option for anyone wanting to take advantage of functional mushrooms' brain-boosting benefits. These capsules contain Lion’s mane, Reishi, Turkey tail, Cordyceps, Maitake, and Chaga, delivering tremendous benefits.

A high-quality mushroom supplement is a simple way to work brain-enhancing nutrients into your daily routine. FreshCap uses only mushroom fruiting bodies and nothing else — just pure mushroom extract made from the best part of the mushroom. There are no grains or fillers; it’s all organic and non-GMO, with everything farmed sustainably.

You can take FreshCap capsules with or without a meal, so they are easy to add to your day at any time you choose.

Shop FreshCap Ultimate Mushroom Complex Capsules here

Naturelo Mushrooms Brain + Immune Blend

bottle of Naturelo Mushrooms Brain and Immune Blend

Naturelo’s blend checks all the boxes for high-quality mushroom supplements. The formula combines three of the most well-researched and revered mushrooms — Lion's mane, Reishi, and Turkey tail — in meaningful, potent amounts.

Naturelo uses standardized organic mushroom extracts derived solely from fruiting bodies to ensure you're getting optimal levels of beneficial compounds like beta-glucans. Too many supplements use lower-quality mycelium (the roots of the mushroom) — and even some of the grain they are grown on — instead.

This mushroom blend provides immune system support from the beta-glucans and polysaccharides in Reishi and Turkey tail, but it really shines in brain health.

Shop Naturelo Mushrooms Brain + Immune Blend here

VitaCup Shroom Fuel

a box of VitaCup Shroom Fuel Drink Mix and Coffee Alternative

If your usual cup of coffee leaves you feeling jittery and burnt out, it's time to try VitaCup's Shroom Fuel. This innovative beverage is shaking up how we get our daily brain boost and improve our cognitive function with a unique blend of medicinal mushrooms and superfood ingredients.

The key ingredients are Lion's mane and Chaga, two mushroom varieties used in traditional medicine for centuries to support brain health and mental clarity.

But Shroom Fuel isn't just another bland mushroom supplement. VitaCup has created a delicious, low-caffeine supplement that makes getting your dose of nootropics a treat.

We're talking about an earthy, lightly sweetened cocoa flavor with hints of cinnamon that's honestly better than a mug of hot chocolate — yet it provides steady, jitter-free energy without the afternoon crash.

Shroom Fuel is a game-changer if you're looking to ditch coffee entirely or just want a healthy coffee alternative for your afternoon pick-me-up. The inventive formula, mouthwatering taste, and brain health benefits make this a supplement you'll look forward to taking daily.

Shop VitaCup Shroom Fuel here


close-up photo of undersides or gills of mushrooms

Are mushrooms really good for brain health?

Certain mushroom varieties are nutritional powerhouses for supporting brain health and cognitive function. Through extensive studies, researchers have uncovered functional mushrooms' impressive brain-boosting and neuroprotective benefits. Healing brain issues can be a lot simpler when you add functional mushrooms to your diet.

What types of mushrooms are good for brain health?

Some top medicinal mushrooms lauded for their brain health and cognitive function-enhancing properties include Lion's mane, Reishi, Cordyceps, and Chaga. Lion's mane mushrooms contain compounds that stimulate nerve growth factors and can enhance mental function, leading to improved focus, better memory, and even neurogenesis (forming new brain cells).

Reishi is packed with antioxidants and anti-inflammatory agents that help protect the brain. Cordyceps enhances oxygen utilization and ATP production to keep those hard-working brain cells fueled. Nutrient-dense Chaga provides a variety of antioxidants crucial for neurological health.

What factors should you consider when choosing the best mushroom supplement for brain health?

When shopping for the best mushroom supplements for focus and cognitive support, pay close attention to the specific mushroom varieties included, and their mushroom extract potency. To ensure quality, look for transparency around exact ingredients, dosages, and third-party testing.

Fruiting body mushroom extracts are superior to mycelium and ground rooting grains. Absorption enhancers can also amplify the effects of beneficial compounds.

Are mushroom supplements for brain health safe for you?

If bought from reputable brands and taken as directed, the top mushroom supplements for brain health are generally considered safe for most healthy adults.

However, they may interact with certain medications or present risks for some people, especially pregnant people and older people. It's always a good idea to consult your doctor before incorporating any new supplement into your routine.

What are the potential side effects of mushroom supplements for brain health?

The most commonly reported functional mushroom side effects result from larger doses and tend to be digestive issues like gas, bloating, or upset stomach. Some people may experience allergic reactions, dizziness, or increased bleeding risks, especially if taking blood thinners simultaneously.

Mushroom supplements can also potentially interfere with diabetes medications by lowering blood sugar levels. Start low and ease your way up to the recommended dosage.


four colleagues working and collaborating on a project in the office

In the realm of natural brain health solutions, mushroom supplements take the cake. The unique compounds in varieties like Lion's mane, Reishi, Cordyceps, and Chaga have continued to impress researchers with the multi-faceted cognitive and neuroprotective benefits they offer.

We're talking real-deal performance enhancers for boosting focus, supercharging memory, and shielding your precious brain cells from oxidative stress and inflammation as you age.

But medicinal mushrooms don't just stop at being brain boosters. Their adaptogenic properties help the mind and body operate like a well-oiled machine, even under the weight of life's inevitable stresses.

If optimizing your brain health and longevity is a priority, ditching the synthetic stuff for high-quality mushroom supplements — especially delicious and effective ones like Goomz Gummies — is a move worth making.

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